Derivation of a No-significant-risk-level (NSRL) for dermal exposures to diethanolamine
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No Significant Risk Level (nsrl) for the Proposition 65 Carcinogen Di(2-ethylhexyl)phthalate
This document provides a basis for the estimation of cancer risk from exposure to di(2 ethylhexyl)phthalate (DEHP). Epidemiological evidence is uninformative with respect to quantitative estimates of cancer risk to humans from exposure to DEHP. There is evidence that DEHP induces liver tumors in rats and mice by a mode of action common to a class of compounds called “peroxisome proliferators,”...
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The human cancer potency of chlorothalonil was estimated and used to calculate a “No Significant Risk Level” (NSRL). The human cancer potency was estimated from doseresponse data for multiple treatment-related tumor sites in male Fischer 344 rats exposed via their feed (Wilson and Killeen, 1989). An overall estimate of cancer potency associated with all treatment-related renal and forestomach t...
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متن کاملNo Significant Risk Level (nsrl) for the Proposition 65 Carcinogen Chlorothalonil
The human cancer potency of chlorothalonil was estimated and used to calculate a “No Significant Risk Level” (NSRL). The human cancer potency was estimated from doseresponse data for multiple treatment-related tumor sites in male Fischer 344 rats exposed via their feed (Wilson and Killeen, 1989). An overall estimate of cancer potency associated with all treatment-related renal and forestomach t...
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ژورنال
عنوان ژورنال: Regulatory Toxicology and Pharmacology
سال: 2016
ISSN: 0273-2300
DOI: 10.1016/j.yrtph.2016.01.020